Fig. 12
From: Creating three dimensional models of Alzheimer’s disease

Comparison of manually-smoothed and auto-segmented hippocampal volumes. Hippocampal volumes are normalized to total intracranial volume. Filled circle = manually-smoothed left hippocampal volume, open circle = auto-segmented left hippocampal volume, filled square = manually-smoothed right hippocampal volume, open square = auto-segmented right hippocampal volume. AD = Alzheimer’s disease. Severe AD-1 = clinically severe Alzheimer’s disease. Severe AD-2 = radiologically severe Alzheimer’s disease